HMPV is not a new virus. It is a well-known pathogen to infectious disease specialists and has been circulating in most countries, including India, for quite some time. As per the CDC, HMPV has a seasonal pattern, circulating in late winter and spring in temperate regions.
Prevalence
Human metapneumovirus (HMPV) is a respiratory virus that can cause severe lower respiratory tract disease with symptoms similar to common cold or flu symptoms.
- HMPV is estimated to cause 5%–25% of respiratory infections in infants and children (2–5 years) and 1.5%–10.5% in adults.
- In children, HMPV is responsible for 5%–15% of hospitalizations for LRTI.
- In adult populations, HMPV is responsible for up to 11% of hospitalizations for acute respiratory illness, particularly in adults with underlying heart or lung disease.
Who Is At Risk?
HMPV can infect anyone, but it poses a higher risk to:
- Older adults, particularly those over 65.
- Children under 5 years old, especially infants.
- Individuals with weakened immune systems or chronic respiratory conditions like asthma or COPD.
How HMPV Spreads?
- Droplets from coughing or sneezing.
- Close contact, such as touching or shaking hands.
- Contaminated surfaces, followed by touching the mouth, nose, or eyes.
Prevention Strategies
- Wash hands frequently with soap and water for at least 20 seconds.
- Avoid touching your face with unwashed hands.
- Wear masks in crowded places during outbreaks.
- Stay home when sick to prevent spreading the virus.
- Basic cough etiquette
- Regularly clean frequently touched surfaces.
Please Note: Currently, it is not a notifiable disease under IDSP.
Diagnosing Tests
- Nucleic acid amplification tests (NAATs) to detect viral genetic material.
- Immunofluorescence or enzyme immunoassays to identify viral antigens.
- Routine testing is rare unless symptoms are severe or there’s an outbreak.
- Confirmation with Biofire Panel Test, which is a high-cost test.
Treatment
There is no specific antiviral treatment or vaccine for HMPV – focus on alleviating symptoms
- Stay hydrated and rest.
- Use over-the-counter (OTC) medications for pain, congestion, and fever.
- Severe cases may require hospitalization for oxygen therapy or intravenous fluids.
- Only contact isolation is recommended. No competent agency has recommended respiratory isolation. Healthcare providers should take standard precautions like any other ailment
For most, HMPV resolves within a week, but young children, older adults, and those with underlying conditions should remain vigilant.
Contact A Healthcare Provider If Symptoms
- Worsen after a few days.
- Include difficulty breathing or cyanosis (bluish skin).
- Occur alongside chronic health conditions like asthma or COPD.
Expert Opinions
As per Global Experts: Based on a probabilistic analysis, the current viral spread is unlikely to result in a COVID like crisis. The reasons for this assessment are twofold:
- Seasonal and Transient Nature- This inherent characteristic of the viruses suggests a natural decline in cases after a short period, unlike the sustained transmission observed with COVID-19’s Delta variant
- Healthcare System Resilience: The healthcare system’s capacity to adapt to seasonal illnesses has been demonstrated historically, and the current situation is expected to be managed within these adaptive responses.
References: Cleveland Clinic, CDC, ICMR, NHM, IDSP Guidelines
While the situation warrants monitoring and appropriate healthcare responses, the probability of a crisis on the scale of the Delta variant pandemic is low.
Dr. Maheshkumar Lakhe
Consultant-Infectious Diseases
Sahyadri Hospitals, Pune
Dr. Raman Gaikwad
Consultant-Infectious Diseases
Sahyadri Hospitals, Pune
Dr. Vaibhav Dudhat
Consultant-Microbiology
Sahyadri Hospitals, Pune