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What is the reason behind Zero Sperm count (Azoospermia)?

Almost 10% of men deal with some form of infertility.

There are multiple reasons for infertility, and Zero Sperm count is one of them.

So what causes this condition? What are the primary reasons for Zero Sperm Count?

We will address these questions in this piece of information.

You can read it further


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What is Zero Sperm Count?

Zero Sperm Count or Azoospermia is a condition in which the semen analysis shows the total absence of sperm.

As this condition has no clear symptoms, it might be shocking for most patients.

So whenever a patient approaches us with this report, we advise them to do some tests. 

These tests include FSH, LH and Testosterone tests. The further treatment plan depends on the results of these tests.

If FSH hormone levels are high, it indicates that the cause of Azoospermia is Testicular Failure.

If the test results show that the FSH level is normal, it indicates that your body produces sperm normally.

But there is some obstruction that’s preventing them from coming out. This condition is known as Obstructive Azoospermia.

Related Read : What is IVF & How is It Done?

What are the Causes of Azoospermia?

Numerous causes can lead to Azoospermia. Here is the list of the primary reasons for Azoospermia.

  • Undescended Testis :

The male testis develops from the child’s abdominal cavity and slowly comes down in the groin.

If the testis fails to descend, this condition is known as Undescended testis. As the stomach temperature is high, the testis’s normal function leads to Azoospermia.

Also, people working in places like furnaces are at a higher risk of Azoospermia.

  • Exposure to Pesticides :

Some pesticides can also impact fertility and lead to Azoospermia.

  • Retrograde Ejaculation :

It’s a condition where the semen ejected via the urethra goes to the urinary bladder instead of coming out. This might lead to Azoospermia.

  • Hormone Deficiency :

In some patients, Hormone deficiency might also lead to Azoospermia.

E.g. Hypogonadotropic Hypogonadism. ing stops. Testis becomes atrophic.

If one testis stays in the stomach and the other descends into the groin, the chances of infertility are very less.

But if both testes are in the abdomen, it can lead to Azoospermia. 

  • Infection :

Different types of infections can lead to Azoospermia.

E.g. a Mumps infection can lead to Azoospermia.

  • Childhood Injury:

Some childhood injuries can cause Azoospermia in some patients.

  • Radiation Treatment:

Multiple Radiation Therapy like the ones for Cancer can also lead to Azoospermia.

  • Exposure to High Temperature :

Exposure to a higher temperature for a longer duration can also cause Azoospermia.

How to Deal with Azoospermia?

Retrograde ejaculation and Hypogonadotropic Hypogonadism are treatable conditions.


For other causes, the patient might need an Assisted Reproductive Technique (ART) like IVF.

At Sahyadri Hospital, we provide all types of ART treatments and help your partner conceive with your own sperm.

But before we proceed with the treatment, we must perform certain tests.

If your FSH and LH levels are normal, we must confirm that your body produces sperm normally. We recommend a testicular biopsy to ensure this.

If we find sperms during the testicular biopsy, we can extract and freeze them for future use. Later, we extract eggs from your partner to perform IVF.

On the same day, we perform a minor procedure for testicular sperm extraction. Later, these sperm are used to fertilize the female’s eggs.

Once the egg fertilizes and an embryo is formed, we implant it in the woman’s uterus.

This way, we can help impregnate your wife with your sperm, even if you have Azoospermia.

Have queries or concern ?

    Closing Thoughts

    Getting Azoospermia in the semen analysis test can be overwhelming for some. But consulting certified fertility specialists can be very helpful.

    They can offer you the right guidance and assist you with your condition.

    We hope this piece of information is quite helpful in understanding Azoospermia and its causes.

    If you are dealing with Azoospermia or know someone who is, feel free to reach out to us. We are always here to help.

    About Author

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    Dr. Aarati Rapol

    Infertility Expert
    Contact: +91 88888 22222
    Email – [email protected]

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